Preheat oven to 450°F. Place rack on upper middle position of oven. Line large rimmed baking sheet with foil and fit oven-safe wire rack inside. Lightly spray the rack with non-stick cooking spray.
Pat dry the chicken, removing as much moisture from the skin as possible.
In a small bowl, mix the baking powder, salt, black pepper, garlic and onion powders and cayenne. Rub mixture over each chicken wing and place on wire rack.
Bake on rack for 30 minutes. Turn wings over and bake an additional 20 minutes. Wings are done when digital meat thermometer reads 165°F when inserted in thickest part of wing. Be careful to avoid the bones.
While wings are cooking, whisk together mayonnaise, yellow mustard, whole grain mustard and honey. Brush over wings during last 5 minutes of baking to glaze.
Mix remaining mustard mixture with mayonnaise to make dipping sauce for the wings.
Serve wings immediately with dipping sauce or ranch dressing.